Semi-quantitative method of N-isopropyl-(123I)-p-iodoamphetamine accumulation in cerebrum: Cerebrum to cerebellum accumulation ratio.
نویسندگان
چکیده
منابع مشابه
Double-injection method for sequentially measuring cerebral blood flow with N-isopropyl-(123I)p-iodoamphetamine.
We investigated the accuracy of a double-injection method for sequentially measuring cerebral blood flow (CBF) with N-isopropyl-(123I)p-iodoamphetamine (IMP) in simulation studies based on patient data and in clinical studies. The unidirectional clearance of IMP from the blood to the brain (K1; nearly equal to CBF) in the first and second sessions was calculated by means of a microsphere model....
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We present a 21-year-old woman with tumefactive multiple sclerosis (MS) that exhibited a rapidly progressive course. There were multiple tumor-mimicking contrast-enhance lesions with surrounding edema and mass effect on magnetic resonance imaging. Both early and delayed brain single photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]-iodoamphetamine demonstrated increased accu...
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N-isopropyl-p[123I]iodoamphetamine, originally designed for brain scintigraphy, has been found to be retained by the normal lung and to produce excellent camera images. Ten patients with gross abnormalities on their chest radiographs due to lung cancer have been studied with this drug. The diseased parts of the lung consistently showed less uptake and these defects matched those obtained with m...
متن کاملDifferential acetylcholinesterase activity in rat cerebrum, cerebellum and hypothalamus.
Acetylcholinesterase (AChE) has been purified from three different regions of rat brain using Sephadex G 200 column. SDS PAGE (6%) showed single band for the purified AChE fractions. Purified and lyophilized AChE from different (NH4)2SO4 precipitated fractions of three brain parts were utilized for in vitro enzyme kinetics using Dimethoate (Dmt) as inhibitor. K(m) values for cerebellum and hypo...
متن کاملN - Isopropyl - p - iodoamphetamine hydrochloride ( IMP ) is predominantly
1 N-Isopropyl-p-iodoamphetamine hydrochloride (IMP) is predominantly metabolized by CYP2C19
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1987
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.36.12_650